Biocomposites materials based on carboxymethyl cellulose/polyethylene glycol/hydroxyapatite for bone regeneration
Khalifi Taghzouti Othman (1)*, El Mabrouk Khalil (1)
(1) Euro-Mediterranean University of Fes - Fès - Morocco
Novel carboxymethyl cellulose/polyethylene glycol/hydroxyapatite (CMC/PEG/HAP) biocomposites based-scaffolds were studied for their ability to nucleate bioactive calcium phosphate crystals for future bone healing applications. Biocomposites were realised via solution casting. The surface morphology and properties of the scaffold were investigated by infrared absorption spectra (IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), mechanical testing and soaking in simulated body fluids (SBF). The results showed a good interaction between three phases. Moreover, the comparison of SEM images of both the scaffolds indicated that the incorporation of PEG influenced the surface morphology while a better in-vitro bioactivity has been recorded in three phases. Also, the CMC/PEG/HAP showed higher mechanical strength compared to CMC-HAP supportive of bone tissue ingrowths.