Bio-based Polyamides (PA6.10, PA10.10 and copolymer PA6.10/6.6) were synthesized by Radici Chimica using renewable resources. Films 50-100micron thick were extruded and mechanical and barrier properties were carried out in order to check the packaging performances. Silica extracted from rice husk and organically modified montmorillonite (Cloisite® 30B) were used in order to obtain biocomposites with improved mechanical performances. The composites were prepared using a twin-screw extruder. A detailed morphological study in terms of adhesion, distribution and dispersion of fillers into the polymeric matrices were carried out. In particular was found a good dispersion degree of fillers in the PA6.10/6.6 copolymer. Thermal, mechanical and thermo-mechanical properties were studied and the Young modulus was increased for the composites in particular with the synergistic effect of silica and Closite 30B used together. Finally in the case of PA6.10 a significant value of storage modulus was obtained also at high temperature (160°C).